My 5s was running fine with Xcode 6.0.1 when I was using iOS 8.0.2. But then I upgraded to iOS 8.1, build my code, and I got an error saying "Xcode cannot run using the selected device. No supported iOS devices are available. Mark an iOS device as 'Use for Development' to run your application or choose an iOS simulator as the destination." So then I figure I need to upgrade to Xcode 6.1, but I still got the same error. The strange thing is under Windows > Devices I can see my iPhone 5s information. Please help, thanks in advance.
I've got the same problem. Just uncheck "Show in Run Destinations Menu" and check it again in Device Window for your device. It works for me.