Is it bad to work with pixels in CSS?
Is it bad in terms of compatibility to use pixel numbers in CSS instead of percentages? How about lower resolutions? Is it okay to work with them in ranges of 1-100?
Answer
This is a difficult question, because the answer mostly depends on your situation.
Pixels are not that bad, I mostly use them too. (Sometimes even for font sizes.)
I usually fix the outer block element of the layout by a given size (pixels with fixed-width layouts, and percentages with fluid layouts), and on the inside elements I usually set percentages whenever possible.
There are some elements which simply can't be styled with percentages or ems, especially the more fancy stuff coming from graphical designers who don't understand such principles.
For example: if you have a column on your site with a simple style, you can set its width to a percentage easily, but if it has a background image with a specific width that is not designed with scaling in mind, it only looks good with a fixed-width. In such cases, you'll have to ensure that the rest of the page occupies the remaining width correctly.
Note that you can use pixels with percentages together.
For example, this is a snippet from one of my latest web apps:
min-width: 800px;
width: 80%;
max-width: 1500px;
The choice also depends on what design or layout you would like to achieve.
For a fixed-width layout, pixel values are fine. If a designer gives you a Photoshop image that contains really fancy stuff which would be extremely complicated to even think about how it would resize, you should definitely go for this.
If your layout needs to be dynamic, you should use percentages to make sure that it expands as the resolution changes, and you can use the above code snippet to make it look better in scenarios where it would otherwise look insane.
Some layouts (eg. imagine if StackOverflow would take up all the space) would look pretty ugly on a width of eg. 1920 pixels - the line widths would be so insanely high that it would be extremely unconvenient to read.
This is what max-width is for. Even in some dynamic layouts, you'll have to limit the maximal width of your site to maximize usability and readability.
And also take into consideration the smaller screens.
It is true that noone uses a 800×600 desktop anymore, but many people browse the web with mobile devices which have even smaller resolution.
This is what min-width is for: to make your dynamically expanded layout look less crowded on smaller resoultions.
I hope this helps.
EDIT:
The Smashing Book has some very nice thoughts about the subject.
EDIT 2:
I don't want my post to sound like I want you to force pixel-based sizing on your visitors.
(Apparently, some people in the comments misunderstood me in such a way.)
To clear it up:
I believe that the ideal layout is one that adjusts well to any possible resolution or setting.
However, we can't always do everything perfectly. Time/resources and the target audience are the key to determine if your site requires that advanced functionality or not.
I'm suggesting that you use the right thing for the given job.
If you are developing a site which will have a significant percentage of visitors who require more advanced adjustments to the site, it may be well worth it.
(Of course, sometimes we just do it for ourselves to have the feeling of doing things the right way, but is is not always a financially sound decision.)
Still, you should do the proper research about what sort of site will be it, who will be the visitors, and such stuff, before deciding about layouts, and whether it is worth the time to make them fluid or more dynamic.