In order to perform a case-sensitive search/replace on a table in a SQL Server 2000/2005 database, you must use the correct collation.
How do you determine whether the default collation for a database is case-sensitive, and if it isn't, how to perform a case-sensitive search/replace?
SELECT testColumn FROM testTable
WHERE testColumn COLLATE Latin1_General_CS_AS = 'example'
SELECT testColumn FROM testTable
WHERE testColumn COLLATE Latin1_General_CS_AS = 'EXAMPLE'
SELECT testColumn FROM testTable
WHERE testColumn COLLATE Latin1_General_CS_AS = 'eXaMpLe'
Don't assume the default collation will be case sensitive, just specify a case sensitive one every time (using the correct one for your language of course)