Is it possible, using Adobe Acrobat or another tool, to globally replace a font in a PDF?
How can I do this?
Replacing a font in a PDF is generally not a good idea. You should not expect behavior similar to replacing a font in e.g. a MS Word document. In PDF, individual glyphs or runs of glyphs are positioned absolutely. At the time the PDF was generated, this positioning was based on the respective widths (and other metrics) of the glyphs in the used font. When you replace a font, the position of the glyphs will remain unchanged, but in general the widths of the glyphs will differ from those in the original font. This will cause distorted text formatting like this: