What is the MultiFrame image in DICOM. How multiframe is different from having multiple images in a single series?
A multi-frame image is typically a more compact representation of a multi-image (single-frame) series. In a single-frame image series, you would need to repeat the same header data (patient information, image properties etc.) in every image; in a multi-frame image the header data is given once.
Multi-frame images inevitably have some limitations in relation to single-frame image series; in particular, all frames in the multi-frame image would need to have the same size, orientation, etc.
Multi-frame images have historically also not been as widely supported by DICOM viewers, PACS systems etc. as single-frame images, although I believe that this situation is improved nowadays.