I haven't found any resources on how to do that. Something as simple as changing the color of the player would be nice to have :)
<audio>
audio::-webkit-media-controls-panel
audio::-webkit-media-controls-mute-button
audio::-webkit-media-controls-play-button
audio::-webkit-media-controls-timeline-container
audio::-webkit-media-controls-current-time-display
audio::-webkit-media-controls-time-remaining-display
audio::-webkit-media-controls-timeline
audio::-webkit-media-controls-volume-slider-container
audio::-webkit-media-controls-volume-slider
audio::-webkit-media-controls-seek-back-button
audio::-webkit-media-controls-seek-forward-button
audio::-webkit-media-controls-fullscreen-button
audio::-webkit-media-controls-rewind-button
audio::-webkit-media-controls-return-to-realtime-button
audio::-webkit-media-controls-toggle-closed-captions-button