How do I unload a DLL which has been loaded using DllImport in C#?
Answer
The most reliable way to unload an unmanaged DLL from a process that got loaded by a [DllImport] pinvoke declaration is to load it yourself, again, by pinvoking LoadLibrary(). That gives you a reliable handle to the DLL and works correctly even if the module name of the DLL is ambiguous. It doesn't have any affect at runtime, other than the Windows loader increasing the internal reference count on the DLL from 1 to 2.
You can then pinvoke FreeLibrary() twice to decrease the reference count to 0, passing it the IntPtr you got from LoadLibrary(). That unloads the DLL, as well as any dependent DLLs that got loaded.
Beware that you'll get very nasty failure when you try to pinvoke any exported function on the DLL again, any time after doing this. The pinvoke marshaller is unaware that the DLL isn't around anymore and will call the function at the address it thinks is still valid. Which bombs your program with an AccessViolation exception if you are lucky. Or runs a completely random bit of code if you are not so lucky and the address space formerly occupied by the DLL got re-used by another DLL. Anything can happen then, none of it good.